Fibroblast Growth Factor 21 Protects Against High Glucose Induced Cellular Damage and Dysfunction of Endothelial Nitric-Oxide Synthase in Endothelial Cells

Fibroblast Growth Factor 21 Protects Against High Glucose Induced Cellular Damage and Dysfunction of Endothelial Nitric-Oxide Synthase in Endothelial Cells

Aims: Fibroblast growth factor 21 (FGF21) is a powerful endocrine hormone modulating glucose and lipid metabolism and represents a promising drug for type 2 diabetes. The present study was to determine the effect of FGF21 on high glucose-induced damage and dysfunction in endothelial cells. Methods:...

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Bibliographic Details
Main Authors: Xiao-Mei Wang, Shuang-Shuang Song, Hang Xiao, Pan Gao, Xue-Jun Li, Liang-Yi Si
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
eNOS
High glucose
FGF21
Endothelial cell
AMPK
Online Access:http://www.karger.com/Article/FullText/363031

Internet

http://www.karger.com/Article/FullText/363031

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