Relaxin Deficiency Leads to Uterine Artery Dysfunction During Pregnancy in Mice

Relaxin Deficiency Leads to Uterine Artery Dysfunction During Pregnancy in Mice

The uterine vasculature undergoes profound adaptations in response to pregnancy. Augmentation of endothelial vasodilator function and reduced smooth muscle reactivity are factors contributing to uterine artery adaptation and are critical for adequate placental perfusion. The peptide hormone relaxin...

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Bibliographic Details
Main Authors: Sarah A. Marshall, Sevvandi N. Senadheera, Maria Jelinic, Kelly O'Sullivan, Laura J. Parry, Marianne Tare
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Physiology
Subjects:
relaxin
pregnancy
uterine artery
myogenic tone
smooth muscle reactivity
endothelium-dependent relaxation
Online Access:http://journal.frontiersin.org/article/10.3389/fphys.2018.00255/full

Internet

http://journal.frontiersin.org/article/10.3389/fphys.2018.00255/full

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