Click Synthesis and Biologic Evaluation of ()- and ()-2-Amino-3-[1-(2-[F]Fluoroethyl)-1-[1,2,3]Triazol-4-yl]Propanoic Acid for Brain Tumor Imaging with Positron Emission Tomography
The ( R )- and ( S )-enantiomers of 2-amino-3-[1-(2-[ 18 F]fluoroethyl)-1 H -[1,2,3]triazol-4-yl]propanoic acid (4) were synthesized and evaluated in the rat 9L gliosarcoma brain tumor model using cell uptake assays, biodistribution studies, and micro-positron emission tomography (microPET). The ( R...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi - SAGE Publishing
2010-11-01
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Series: | Molecular Imaging |
Online Access: | https://doi.org/10.2310/7290.2010.00025 |