T Cell Response to Infliximab in Exposed Patients: A Longitudinal Analysis

T Cell Response to Infliximab in Exposed Patients: A Longitudinal Analysis

This study aimed to evaluate the proportion of infliximab (IFX)-exposed patients exhibiting cellular response to the drug in a longitudinal way and to establish whether it is predictive for anti-drug antibodies (ADA) development. Seventeen patients suffering from immuno-mediated disorders were enrol...

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Bibliographic Details
Main Authors: Sara Pratesi, Francesca Nencini, Francesca Grosso, Laura Dies, Susanna Bormioli, Daniele Cammelli, Enrico Maggi, Andrea Matucci, Alessandra Vultaggio, ABIRISK Consortium
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Immunology
Subjects:
anti-drug antibodies
IL-10
immunogenicity
infliximab
IFX-specific T cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.03113/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.03113/full

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