Role of pyruvate kinase M2 in oxidized LDL-induced macrophage foam cell formation and inflammation[S]

Pyruvate kinase M2 (PKM2) links metabolic and inflammatory dysfunction in atherosclerotic coronary artery disease; however, its role in oxidized LDL (Ox-LDL)-induced macrophage foam cell formation and inflammation is unknown and therefore was studied. In recombinant mouse granulocyte-macrophage colo...

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Bibliographic Details
Main Authors: Amit Kumar, Priya Gupta, Minakshi Rana, Tulika Chandra, Madhu Dikshit, Manoj Kumar Barthwal
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520435199