Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

Quantitative ELISAs for serum soluble LHCGR and hCG-LHCGR complex: potential diagnostics in first trimester pregnancy screening for stillbirth, Down’s syndrome, preterm delivery and preeclampsia

<p>Abstract</p> <p>Background</p> <p>Soluble LH/hCG receptor (sLHCGR) released from placental explants and transfected cells can be detected in sera from pregnant women. To determine whether sLHCGR has diagnostic potential, quantitative ELISAs were developed and tested...

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Bibliographic Details
Main Authors: Chambers Anne E, Griffin Christopher, Naif Samantha A, Mills Ian, Mills Walter E, Syngelaki Argyro, Nicolaides Kypros H, Banerjee Subhasis
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Reproductive Biology and Endocrinology
Subjects:
LHCGR
ELISA
Down’s syndrome
Stillbirth
Preeclampsia
Preterm delivery
Early pregnancy
Online Access:http://www.rbej.com/content/10/1/113

Internet

http://www.rbej.com/content/10/1/113

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