Clinical Application of Whole Exome Sequencing for Monogenic Disorders in PICU of China

Clinical Application of Whole Exome Sequencing for Monogenic Disorders in PICU of China

ObjectivesWhole exome sequencing (WES) has been widely used to detect genetic disorders in critically ill children. Relevant data are lacking in pediatric intensive care units (PICUs) of China. This study aimed to investigate the spectrum of monogenic disorders, the diagnostic yield and clinical uti...

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Bibliographic Details
Main Authors: Yingchao Liu, Chanjuan Hao, Kechun Li, Xuyun Hu, Hengmiao Gao, Jiansheng Zeng, Ruolan Guo, Jun Liu, Jun Guo, Zheng Li, Zhan Qi, Xinlei Jia, Wei Li, Suyun Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
whole exome sequence
pediatric intensive care unit
monogenic disorders
clinical application
effective
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.677699/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.677699/full

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