Synthesis and antinociceptive activity of novel mannich base derivatives of some new fused 3,5-pyrazolidinedione
In the present study, a novel series of mannich bases 1-((1-substituted ethyl-1H-benzo[d] imidazol-2-yl) methyl)-2-substituted phenylpyrazolidine-3,5-dione 3(a-l) were synthesized and evaluated as antinociceptive agents in mice by Eddy′s hot plate and acetic acid-induced writhing models. The structu...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Advanced Pharmaceutical Technology & Research |
| Subjects: | |
| Online Access: | http://www.japtr.org/article.asp?issn=2231-4040;year=2014;volume=5;issue=1;spage=41;epage=47;aulast=Tiwari |