Haem relieves hyperoxia-mediated inhibition of HMEC-1 cell proliferation, migration and angiogenesis by inhibiting BACH1 expression

Abstract Background Hyperoxia-mediated inhibition of vascular endothelial growth factor (VEGF) in the retina is the main cause of impeded angiogenesis during phase I retinopathy of prematurity (ROP). Human retinal angiogenesis involves the proliferation, migration and vessel-forming ability of micro...

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Bibliographic Details
Main Authors: Lan Jian, Yang Mei, Chen Xing, Yuan Rongdi
Format: Article
Language:English
Published: BMC 2021-02-01
Series:BMC Ophthalmology
Subjects:
Online Access:https://doi.org/10.1186/s12886-021-01866-x