Synthesis and Antiplasmodial Activity of 3-Furyl and 3-Thienylquinoxaline-2-carbonitrile 1,4-Di-N-oxide Derivatives
The aim of this study was to identify new compounds active againstPlasmodium falciparum based on our previous research carried out on 3-phenylquinoxaline-2-carbonitrile 1,4-di-N-oxide derivatives. Twelve compounds weresynthesized and evaluated for antimalarial activity. Eight of them showed an IC50...
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Bibliographic Details
Main Authors: |
Antonio Monge,
Livia Vivas,
Ignacio Aldana,
Silvia Pérez-Silanes,
Saioa Ancizu,
Beatriz Solano,
Asunción Burguete,
Raquel Villar,
Emily Bongard,
Sarah Charnaud,
Esther Vicente |
Format: | Article
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Language: | English |
Published: |
MDPI AG
2008-01-01
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Series: | Molecules
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Subjects: |
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Online Access: | http://www.mdpi.com/1420-3049/13/1/69/
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