Primaquine–quinoxaline 1,4-di-N-oxide hybrids with action on the exo-erythrocytic forms of Plasmodium induce their effect by the production of reactive oxygen species

by Leonardo Bonilla-Ramírez, Silvia Galiano, Miguel Quiliano, Ignacio Aldana, Adriana Pabón
Published 2019-06-01

The in vivo antimalarial activity of methylene blue combined with pyrimethamine, chloroquine and quinine

by Giovanny Garavito, Stéphane Bertani, Miguel Quiliano, Alexis Valentin, Ignacio Aldana, Eric Deharo
Published 2012-09-01

An easy and direct method for the synthesis of 1,2,4-triazole derivatives through carboxylic acids and hydrazinophthalazine

by Gildardo Rivera, Virgilio Bocanegra-Garcia, Antonio Moreno, Silvia Galiano, Silvia Pérez, Ignacio Aldana, Antonio Monge
Published 2008-01-01

Unexpected Reduction of Ethyl 3-Phenylquinoxaline-2- carboxylate 1,4-Di-N-oxide Derivatives by Amines

by Antonio Monge, Ignacio Aldana, Silvia Pérez-Silanes, Beatriz Solano, Esther Vicente, Lidia M. Lima
Published 2008-01-01

New Amide Derivatives of Quinoxaline 1,4-di-N-Oxide with Leishmanicidal and Antiplasmodial Activities

by Eric Deharo, German Gonzalez, Antonio Monge, Silvia Pérez-Silanes, Silvia Galiano, Carlos Barea, Adriana Pabón, Ignacio Aldana
Published 2013-04-01

Synthesis, Biological Evaluation and Structure-Activity Relationships of New Quinoxaline Derivatives as Anti-Plasmodium falciparum Agents

by Ana Gil, Adriana Pabón, Silvia Galiano, Asunción Burguete, Silvia Pérez-Silanes, Eric Deharo, Antonio Monge, Ignacio Aldana
Published 2014-02-01

Studies on Log Po/w of Quinoxaline di-N-Oxides: A Comparison of RP-HPLC Experimental and Predictive Approaches

by James A. Platts, Antonio Monge, Ignacio Aldana, Mauro Ravera, Enrique Torres, Silvia Pérez-Silanes, Elisabetta Gabano, Elsa Moreno
Published 2011-09-01

New Quinoxaline Derivatives as Potential MT<sub>1</sub> and MT<sub>2</sub> Receptor Ligands

by Saioa Ancizu, Nerea Castrillo, Silvia Pérez-Silanes, Ignacio Aldana, Antonio Monge, Philippe Delagrange, Daniel-Henry Caignard, Silvia Galiano
Published 2012-06-01

Antiplasmodial and Leishmanicidal Activities of 2-Cyano-3-(4-phenylpiperazine-1-carboxamido) Quinoxaline 1,4-Dioxide Derivatives

by Carlos Barea, Adriana Pabón, Silvia Galiano, Silvia Pérez-Silanes, German Gonzalez, Chloe Deyssard, Antonio Monge, Eric Deharo, Ignacio Aldana
Published 2012-08-01

New antagonist agents of neuropeptide y receptors

by Ignacio Aldana, Isabel Rivero, Argimiro Rivero, Patricio Huenchuñir, Carmen Frigola, Maria Luisa Alonso, Antonio Monge, D. H. Caignard, P. Renard
Published 2000-12-01

Substitutions of Fluorine Atoms and Phenoxy Groups in the Synthesis of Quinoxaline 1,4-di-N-oxide Derivatives

by Antonio Monge, Ignacio Aldana, Silvia Pérez-Silanes, Saioa Ancizu, Beatriz Solano, Asunción Burguete, Raquel Villar, Esther Vicente
Published 2008-01-01

Anti-leishmanial and structure-activity relationship of ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives

by Asunción Burguete, Yannick Estevez, Denis Castillo, Germán González, Raquel Villar, Beatriz Solano, Esther Vicente, Silvia Pérez Silanes, Ignacio Aldana, Antonio Monge, Michel Sauvain, Eric Deharo
Published 2008-12-01

Heterocyclic-2-carboxylic Acid (3-Cyano-1,4-di-N-oxidequinoxalin-2-yl)amide Derivatives as Hits for the Development of Neglected Disease Drugs

by Antonio Monge, Mercedes González, Hugo Cerecetto, Beatriz Solano, Ignacio Aldana, Adoración Marín, Raquel Villar, Diego Benítez, Silvia Pérez-Silanes, Asunción Burguete, Saioa Ancizu, Elsa Moreno, Enrique Torres
Published 2009-06-01

Synthesis and Antiplasmodial Activity of 3-Furyl and 3-Thienylquinoxaline-2-carbonitrile 1,4-Di-N-oxide Derivatives

by Antonio Monge, Livia Vivas, Ignacio Aldana, Silvia Pérez-Silanes, Saioa Ancizu, Beatriz Solano, Asunción Burguete, Raquel Villar, Emily Bongard, Sarah Charnaud, Esther Vicente
Published 2008-01-01

New 1-Aryl-3-Substituted Propanol Derivatives as Antimalarial Agents

by Antonio Monge, Ignacio Aldana, Juan J. Nogal-Ruiz, Antonio R. Martínez-Fernández, Berta Martín Pérez-Solórzano, Silvia Galiano, Adela Mendoza, Silvia Pérez-Silanes, Luis Berrade, Rory N. García–Sánchez
Published 2009-10-01

Exploring the scope of new arylamino alcohol derivatives: Synthesis, antimalarial evaluation, toxicological studies, and target exploration

by Miguel Quiliano, Adela Mendoza, Kim Y. Fong, Adriana Pabón, Nathan E. Goldfarb, Isabelle Fabing, Ariane Vettorazzi, Adela López de Cerain, Ben M. Dunn, Giovanny Garavito, David W. Wright, Eric Deharo, Silvia Pérez-Silanes, Ignacio Aldana, Silvia Galiano
Published 2016-12-01