Cell cycle regulation of DNA polymerase beta in rotenone-based Parkinson's disease models.

In Parkinson's disease (PD), neuronal cells undergo mitotic catastrophe and endoreduplication prior to cell death; however, the regulatory mechanisms remain to be defined. In this study, we investigated cell cycle regulation of DNA polymerase β (poly β) in rotenone-based dopaminergic cellular a...

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Bibliographic Details
Main Authors: Hongcai Wang, Yan Chen, Jinbo Chen, Zhentao Zhang, Wansheng Lao, Xizhi Li, Jinsha Huang, Tao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4193828?pdf=render