ENPP1-Fc prevents neointima formation in generalized arterial calcification of infancy through the generation of AMP

Arterial disease: promising protein replacement therapy in inherited disorder A protein replacement therapy may prove useful in tackling calcification and narrowing of the arteries in babies with a severe genetic disorder. Generalized Arterial Calcification of Infancy (GACI) is a rare condition in w...

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Bibliographic Details
Main Authors: Yvonne Nitschke, Yan Yan, Insa Buers, Kristina Kintziger, Kim Askew, Frank Rutsch
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-018-0163-5