Emerging cellular functions of cytoplasmic PML

Emerging cellular functions of cytoplasmic PML

The tumor suppressor promyelocytic leukaemia protein (PML) is located primarily in the nucleus, where it is the scaffold component of the PML nuclear bodies (PML-NBs). PML-NBs regulate multiple cellular functions, such as apoptosis, senescence, DNA damage response and resistance to viral infection....

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Bibliographic Details
Main Authors: Guoxiang eJin, YIng-Jan eWang, Hui-Kuan eLin
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-06-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
tumorigenesis
TGF-β
Cytoplasmic PML
antiviral response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00147/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2013.00147/full

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