Evaluation of strategies for the assembly of diverse bacterial genomes using MinION long-read sequencing

Evaluation of strategies for the assembly of diverse bacterial genomes using MinION long-read sequencing

Abstract Background Short-read sequencing technologies have made microbial genome sequencing cheap and accessible. However, closing genomes is often costly and assembling short reads from genomes that are repetitive and/or have extreme %GC content remains challenging. Long-read, single-molecule sequ...

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Bibliographic Details
Main Authors: Sarah Goldstein, Lidia Beka, Joerg Graf, Jonathan L. Klassen
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Genomics
Subjects:
Oxford Nanopore MinION
Genome sequencing
Genome assembly
Secondary metabolites
Insertion sequences
Online Access:http://link.springer.com/article/10.1186/s12864-018-5381-7

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http://link.springer.com/article/10.1186/s12864-018-5381-7

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