HDAC1 controls CD8+ T cell homeostasis and antiviral response.

HDAC1 controls CD8+ T cell homeostasis and antiviral response.

Reversible lysine acetylation plays an important role in the regulation of T cell responses. HDAC1 has been shown to control peripheral T helper cells, however the role of HDAC1 in CD8+ T cell function remains elusive. By using conditional gene targeting approaches, we show that LckCre-mediated dele...

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Bibliographic Details
Main Authors: Roland Tschismarov, Sonja Firner, Cristina Gil-Cruz, Lisa Göschl, Nicole Boucheron, Günter Steiner, Patrick Matthias, Christian Seiser, Burkhard Ludewig, Wilfried Ellmeier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4204873?pdf=render

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http://europepmc.org/articles/PMC4204873?pdf=render

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