Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations

Abstract Background Asthma is a heterogeneous chronic airway disease, which may be classified into different phenotypes. YKL-40 is a chitin-binding glycoprotein with unclear functions, but its expression is associated with inflammation and tissue remodeling. However, few studies have explored whethe...

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Bibliographic Details
Main Authors: Lei Liu, Xin Zhang, Ying Liu, Li Zhang, Jing Zheng, Ji Wang, Philip M. Hansbro, Lei Wang, Gang Wang, Alan Chen-Yu Hsu
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-019-1051-9