An increase in myocardial 18-fluorodeoxyglucose uptake is associated with left ventricular ejection fraction decline in Hodgkin lymphoma patients treated with anthracycline

An increase in myocardial 18-fluorodeoxyglucose uptake is associated with left ventricular ejection fraction decline in Hodgkin lymphoma patients treated with anthracycline

Abstract Background Doxorubicin (DOX)-based chemotherapy for Hodgkin lymphoma (HL) yields excellent disease-free survival, but poses a substantial risk of subsequent left ventricular (LV) dysfunction and heart failure, typically with delayed onset. At the cellular level, this cardiotoxicity includes...

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Bibliographic Details
Main Authors: Matteo Sarocchi, Matteo Bauckneht, Eleonora Arboscello, Selene Capitanio, Cecilia Marini, Silvia Morbelli, Maurizio Miglino, Angela Giovanna Congiu, Giorgio Ghigliotti, Manrico Balbi, Claudio Brunelli, Gianmario Sambuceti, Pietro Ameri, Paolo Spallarossa
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Journal of Translational Medicine
Subjects:
Doxorubicin
Cardiotoxicity
18FDG-PET
Left ventricular dysfunction
Heart failure
Online Access:http://link.springer.com/article/10.1186/s12967-018-1670-9

Internet

http://link.springer.com/article/10.1186/s12967-018-1670-9

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