Comparison of real time IS6110-PCR, microscopy, and culture for diagnosis of tuberculous meningitis in a cohort of adult patients in Indonesia.

BACKGROUND: Bacteriological confirmation of tuberculous (TB) meningitis is difficult. Culture is slow and microscopy has insufficient sensitivity. We evaluated real time PCR targeting insertion sequence IS6110 among 230 consecutive adult patients with subacute meningitis in a referral hospital in In...

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Main Authors: Lidya Chaidir, Ahmad Rizal Ganiem, Adri Vander Zanden, Soni Muhsinin, Tina Kusumaningrum, Inri Kusumadewi, Andre van der Ven, Bachti Alisjahbana, Ida Parwati, Reinout van Crevel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3528723?pdf=render