EphB4 inhibitor overcome the acquired resistance to cisplatin in melanomas xenograft model

The purpose of this paper is to investigate the possible mechanisms of resistance to chemotherapy in melanoma from the perspective of molecular biology and to discuss the strategies to overcome them. Cisplatin, a DNA-damaging compound that triggers apoptotic cell death, is commonly used in the treat...

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Bibliographic Details
Main Authors: Xiaokun Yang, Yadong Yang, Shuqian Tang, Hui Tang, Guihong Yang, Qiaoyu Xu, Jinjin Wu
Format: Article
Language:English
Published: Elsevier 2015-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315001929