Positive feedback between retinoic acid and 2-phospho-L-ascorbic acid trisodium salt during somatic cell reprogramming

Positive feedback between retinoic acid and 2-phospho-L-ascorbic acid trisodium salt during somatic cell reprogramming

Abstract Retinoic acid (RA) and 2-phospho-L-ascorbic acid trisodium salt (AscPNa) promote the reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells. In the current studies, the lower abilities of RA and AscPNa to promote reprogramming in the presence of each other suggested...

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Bibliographic Details
Main Authors: Mengdan Zhang, Qian Li, Tingting Yang, Fei Meng, Xiaowei Lai, Lining Liang, Changpeng Li, Hao Sun, Jiaqi Sun, Hui Zheng
Format: Article
Language:English
Published: SpringerOpen 2020-10-01
Series:Cell Regeneration
Subjects:
Reprogramming
L-ascorbic acid
Retinoic acid
Positive feedback
Mesenchymal-epithelial transition
Online Access:http://link.springer.com/article/10.1186/s13619-020-00057-1

Internet

http://link.springer.com/article/10.1186/s13619-020-00057-1

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