Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila

Intergenerational inheritance of high fat diet-induced cardiac lipotoxicity in Drosophila

Animal studies have shown that the nutritional status of parents can predispose the offspring to obesity and obesity-related diseases. Here the authors show that cardiac dysfunction induced by a high-fat diet persists for two generations in Drosophila, and that targeted expression of ATGL/bmm in the...

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Bibliographic Details
Main Authors: Maria Clara Guida, Ryan Tyge Birse, Alessandra Dall’Agnese, Paula Coutinho Toto, Soda Balla Diop, Antonello Mai, Peter D. Adams, Pier Lorenzo Puri, Rolf Bodmer
Format: Article
Language:English
Published: Nature Publishing Group 2019-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-08128-3

Internet

https://doi.org/10.1038/s41467-018-08128-3

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