Visfatin promotes intervertebral disc degeneration by inducing IL-6 expression through the ERK/JNK/p38 signalling pathways

Visfatin promotes intervertebral disc degeneration by inducing IL-6 expression through the ERK/JNK/p38 signalling pathways

Visfatin reportedly induces the expression of proinflammatory cytokines. Severe grades of intervertebral disc disease (IVDD) exhibit higher expression of visfatin than mild ones. However, the direct relationship between visfatin and IVDD remains to be elucidated. This study aimed to clarify whether...

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Bibliographic Details
Main Authors: Haitao Cui, Xianfa Du, Caijun Liu, Shunlun Chen, Haowen Cui, Hui Liu, Jianru Wang, Zhaomin Zheng
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Adipocyte
Subjects:
adipocytokine
visfatin
il-6
aggrecan
type ii collagen
ivdd
Online Access:http://dx.doi.org/10.1080/21623945.2021.1910155

Internet

http://dx.doi.org/10.1080/21623945.2021.1910155

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