Non-peptide furin inhibitors based on amidinohydrazones of diarylaldehydes

A series of novel non-peptidic furin inhibitors containing amidinohydrazone moieties has been synthesized under interaction of dialdehydes, the derivatives of ethylene diethylvanillin ethers, with aminoguanidine bicarbonate. Two aryl cycles were bridged by 1,2-ethylene-, 1,4-buthylene- or 1,4-dimeth...

Full description

Bibliographic Details
Main Authors: V. K. Kibirev, T. V. Osadchuk, O. P. Kozachenko, O. B. Vadzyuk, V. S. Brovarets
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2013-02-01
Series:Ukrainian Biochemical Journal
Subjects:
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/07/Kibirev_1_13.pdf