Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury

Immunomodulatory and Antiviral Activity of Metformin and Its Potential Implications in Treating Coronavirus Disease 2019 and Lung Injury

The pandemic of coronavirus disease 2019 (COVID-19), a disease which causes severe lung injury and multiple organ damage, presents an urgent need for new drugs. The case severity and fatality of COVID-19 are associated with excessive inflammation, namely, a cytokine storm. Metformin, a widely used d...

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Bibliographic Details
Main Authors: Xianyang Chen, Huifang Guo, Li Qiu, Chengdong Zhang, Qiang Deng, Qibin Leng
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
coronavirus disease 2019
SARS-CoV-2
cytokine storm
metformin
antiviral activity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02056/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02056/full

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