Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis

Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis

Abstract Background Giant cell arteritis (GCA) is the most common form of vasculitis affecting elderly people. It is one of the few true ophthalmic emergencies but symptoms and signs are variable thereby making it a challenging disease to diagnose. A temporal artery biopsy is the gold standard to co...

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Bibliographic Details
Main Authors: Elisabeth De Smit, Samuel W. Lukowski, Lisa Anderson, Anne Senabouth, Kaisar Dauyey, Sharon Song, Bruce Wyse, Lawrie Wheeler, Christine Y. Chen, Khoa Cao, Amy Wong Ten Yuen, Neil Shuey, Linda Clarke, Isabel Lopez Sanchez, Sandy S. C. Hung, Alice Pébay, David A. Mackey, Matthew A. Brown, Alex W. Hewitt, Joseph E. Powell
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Medical Genomics
Subjects:
Giant cell arteritis
Disease biomarkers
RNA sequencing
Expression profiling
Transcriptome
CD4 & CD8 T lymphocytes
Online Access:http://link.springer.com/article/10.1186/s12920-018-0376-4

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http://link.springer.com/article/10.1186/s12920-018-0376-4

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