Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity[S]

Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity[S]

Recent studies demonstrate that HDL's ability to promote cholesterol efflux from macrophages associates strongly with cardioprotection in humans independently of HDL-cholesterol (HDL-C) and apoA-I, HDL's major protein. However, the mechanisms that impair cholesterol efflux capacity during...

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Bibliographic Details
Main Authors: Tomáš Vaisar, Chongren Tang, Ilona Babenko, Patrick Hutchins, Jake Wimberger, Anthony F. Suffredini, Jay W. Heinecke
Format: Article
Language:English
Published: Elsevier 2015-08-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
apolipoproteins
high density lipoprotein
inflammation
mass spectrometry
proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520355292

Internet

http://www.sciencedirect.com/science/article/pii/S0022227520355292

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