Genetic and epigenetic differences of benign and malignant pheochromocytomas and paragangliomas (PPGLs)

Pheochromocytomas and paragangliomas (PPGLs) are tumors arising from the adrenal medulla and sympathetic/parasympathetic paraganglia, respectively. According to Th e Cancer Genome Atlas (TCGA), approximately 40% of PPGLs are due to germ line mutations in one of 16 susceptibility genes, and a further...

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Bibliographic Details
Main Authors: Khatami Fatemeh, Mohammadamoli Mahsa, Tavangar Seyed Mohammad
Format: Article
Language:English
Published: Sciendo 2018-01-01
Series:Endocrine Regulations
Subjects:
Online Access:https://doi.org/10.2478/enr-2018-0006