Hepatitis C Virus Non-Structural Protein 5A (NS5A) Disrupts Mitochondrial Dynamics and Induces Mitophagy

Mitophagy is a selective form of autophagy, targeting damaged mitochondria for lysosomal degradation. Although HCV infection has been shown to induce mitophagy, the precise underlying mechanism and the effector protein responsible remain unclear. Herein, we demonstrated that the HCV non-structural p...

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Bibliographic Details
Main Authors: Alagie Jassey, Ching-Hsuan Liu, Chun A. Changou, Christopher D. Richardson, Hsue-Yin Hsu, Liang-Tzung Lin
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
HCV
Online Access:https://www.mdpi.com/2073-4409/8/4/290