Reproducibility of GMP-compliant production of therapeutic stressed peripheral blood mononuclear cell-derived secretomes, a novel class of biological medicinal products
Abstract Background The recent concept of secretome-based tissue regeneration has profoundly altered the field of regenerative medicine and offers promising novel therapeutic options. In contrast to medicinal products with a single active substance, cell-derived secretomes comprise pleiotropic bioac...
Main Authors: | Maria Laggner, Alfred Gugerell, Christiane Bachmann, Helmut Hofbauer, Vera Vorstandlechner, Marcus Seibold, Ghazaleh Gouya Lechner, Anja Peterbauer, Sibylle Madlener, Svitlana Demyanets, Dirk Sorgenfrey, Tobias Ostler, Michael Erb, Michael Mildner, Hendrik Jan Ankersmit |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-01-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-019-1524-2 |
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