UDiTaS™, a genome editing detection method for indels and genome rearrangements

UDiTaS™, a genome editing detection method for indels and genome rearrangements

Abstract Background Understanding the diversity of repair outcomes after introducing a genomic cut is essential for realizing the therapeutic potential of genomic editing technologies. Targeted PCR amplification combined with Next Generation Sequencing (NGS) or enzymatic digestion, while broadly use...

Full description

Bibliographic Details
Main Authors: Georgia Giannoukos, Dawn M. Ciulla, Eugenio Marco, Hayat S. Abdulkerim, Luis A. Barrera, Anne Bothmer, Vidya Dhanapal, Sebastian W. Gloskowski, Hariharan Jayaram, Morgan L. Maeder, Maxwell N. Skor, Tongyao Wang, Vic E. Myer, Christopher J. Wilson
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Genomics
Subjects:
Gene editing
CRISPR/CAS9
Next generation sequencing
NGS
UDiTaS
Translocation detection
Online Access:http://link.springer.com/article/10.1186/s12864-018-4561-9

Internet

http://link.springer.com/article/10.1186/s12864-018-4561-9

Similar Items