Increased effort during partial ventilatory support is not associated with lung damage in experimental acute lung injury

Abstract Background An on-going debate exists as to whether partial ventilatory support is lung protective in an acute phase of ARDS. So far, the effects of different respiratory efforts on the development of ventilator-associated lung injury (VALI) have been poorly understood. To test the hypothesi...

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Bibliographic Details
Main Authors: Dietrich Henzler, Alf Schmidt, Zhaolin Xu, Nada Ismaiel, Haibo Zhang, Arthur S. Slutsky, Paolo Pelosi
Format: Article
Language:English
Published: SpringerOpen 2019-11-01
Series:Intensive Care Medicine Experimental
Subjects:
ALI
Online Access:http://link.springer.com/article/10.1186/s40635-019-0272-z