Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication

Summary: To ensure a successful infection, herpesviruses have developed elegant strategies to counterbalance the host anti-viral responses. Sterile alpha motif and HD domain 1 (SAMHD1) was recently identified as an intrinsic restriction factor for a variety of viruses. Aside from HIV-2 and the relat...

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Bibliographic Details
Main Authors: Kun Zhang, Dong-Wen Lv, Renfeng Li
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719304851