Striatal circuit development and its alterations in Huntington's disease

Huntington's disease (HD) is an inherited neurodegenerative disorder that usually starts during midlife with progressive alterations of motor and cognitive functions. The disease is caused by a CAG repeat expansion within the huntingtin gene leading to severe striatal neurodegeneration. Recent...

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Bibliographic Details
Main Authors: Margaux Lebouc, Quentin Richard, Maurice Garret, Jérôme Baufreton
Format: Article
Language:English
Published: Elsevier 2020-11-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612030351X