DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia

Sustained sperm production is dependent on activity of undifferentiated spermatogonia. Here, the authors demonstrate an essential role for RNA helicase DDX5 in maintenance of spermatogonia in adults through control of gene transcription plus RNA processing and export.

Bibliographic Details
Main Authors: Julien M. D. Legrand, Ai-Leen Chan, Hue M. La, Fernando J. Rossello, Minna-Liisa Änkö, Frances V. Fuller-Pace, Robin M. Hobbs
Format: Article
Language:English
Published: Nature Publishing Group 2019-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09972-7

Internet

https://doi.org/10.1038/s41467-019-09972-7

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