Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS-Induced Ulcerative Colitis Through Antispasmodic Effect and Anti-Inflammation

Desmethylbellidifolin From Gentianella acuta Ameliorate TNBS-Induced Ulcerative Colitis Through Antispasmodic Effect and Anti-Inflammation

Desmethylbellidifolin (DMB) is a natural xanthone extracted from Gentianella acuta, which is used as the antidiarrhea drug in traditional Mongolian medicines. It remains unknown whether DMB can ameliorate ulcerative colitis (UC). In this study, trinitrobenzenesulfonic acid (TNBS)-induced colitis rat...

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Bibliographic Details
Main Authors: Yajuan Ni, Mengyang Liu, Haiyang Yu, Yue Chen, Yanxia Liu, Suyile Chen, Jingya Ruan, Alatengchulu Da, Yi Zhang, Tao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Pharmacology
Subjects:
Gentianella acuta
ulcerative colitis
desmethylbellidifolin
inflammation
intestine contraction
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01104/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.01104/full

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