Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis

Abstract Tumourigenic tissue uses modified metabolic signalling pathways in order to support hyperproliferation and survival. Cancer-associated aerobic glycolysis resulting in lactic acid production was described nearly 100 years ago. Furthermore, increased reactive oxygen species (ROS) and lactate...

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Bibliographic Details
Main Authors: Mokgadi Violet Gwangwa, Anna Margaretha Joubert, Michelle Helen Visagie
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:http://link.springer.com/article/10.1186/s11658-018-0088-y