METHODOLOGICAL APPROACHES TO MYCOBACTERIUM TUBERCULOSIS GENOTYPING FOR EVOLUTIONARY AND EPIDEMIOLOGICAL RESEARCH

METHODOLOGICAL APPROACHES TO MYCOBACTERIUM TUBERCULOSIS GENOTYPING FOR EVOLUTIONARY AND EPIDEMIOLOGICAL RESEARCH

Abstract. Current genome evolution of Mycobacterium tuberculosis is marked by virtual absence of the lateral gene transfer leading to the clonal population of this species consisting of separate genetic families. Standard typing method of M. tuberculosis (IS6110-RFLP, spoligo- and VNTR-typing) are b...

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Bibliographic Details
Main Author: I. V. Mokrousov
Format: Article
Language:Russian
Published: Sankt-Peterburg : NIIÈM imeni Pastera 2014-07-01
Series:Infekciâ i Immunitet
Subjects:
mycobacterium tuberculosis
evolution
molecular epidemiology
genotyping
is6110
deletions
polymorphism
vntr
crispr
Online Access:https://www.iimmun.ru/iimm/article/view/76

Internet

https://www.iimmun.ru/iimm/article/view/76

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