Biochemical phenotyping of multiple myeloma patients at diagnosis reveals a disorder of mitochondrial complexes I and II and a Hartnup-like disturbance as underlying conditions, also influencing different stages of the disease

Biochemical phenotyping of multiple myeloma patients at diagnosis reveals a disorder of mitochondrial complexes I and II and a Hartnup-like disturbance as underlying conditions, also influencing different stages of the disease

Abstract The aim of this study was to identify novel plasma metabolic signatures with possible relevance during multiple myeloma (MM) development and progression. A biochemical quantitative phenotyping platform based on targeted electrospray ionization tandem mass spectrometry technology was used to...

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Bibliographic Details
Main Authors: Ismael Dale Cotrim Guerreiro da Silva, Erica Valadares de Castro Levatti, Amanda Paula Pedroso, Dirce Maria Lobo Marchioni, Antonio Augusto Ferreira Carioca, Gisele Wally Braga Colleoni
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-75862-4

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https://doi.org/10.1038/s41598-020-75862-4

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