Association between Altered Expression and Genetic Variations of Transforming Growth Factor β-Smad Pathway with Chronic Myeloid Leukemia

Association between Altered Expression and Genetic Variations of Transforming Growth Factor β-Smad Pathway with Chronic Myeloid Leukemia

Background: Chronic myeloid leukemia (CML) is a hematological disorder caused by fusion of BCR and ABL genes. BCR-ABL dependent and independent pathways play equally important role in CML. TGFβ-Smad pathway, an important BCR -ABL independent pathway, has scarce data in CML. Present study investigat...

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Bibliographic Details
Main Authors: Yogender Shokeen, Neeta Raj Sharma, Abhishek Vats, Veronique Dinand, Mirza Adil Beg, Satish Sanskaran, Sachin Minhas, Mayank Jauhri, Arun K Hariharan, Vibha Taneja, Shyam Aggarwal
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2018-01-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Chronic myeloid leukemia (CML)
SMAD
SMAD7
TGFβ-Smad pathway
TGFβ1
TGFβR1
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/758

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/758

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