The changes of mitochondrial cytochrome c and GABAergic neuron in neuropathic pain model

BackgroundRole of cytochrome c (Cyt c) is an apoptogenic agent under certain conditions. The mitochondrial permeability transition pore (MPTP) plays an important role in cell death since it opens, leading to mitochondrial swelling and release of Cyt c, which initiates apoptosis. By inhibiting the op...

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Bibliographic Details
Main Authors: Won Sung Kim, Ju Yeon Park, Tae Kyun Kim, Seong Wan Baik
Format: Article
Language:English
Published: Korean Society of Anesthesiologists 2012-04-01
Series:Korean Journal of Anesthesiology
Subjects:
Online Access:http://ekja.org/upload/pdf/kjae-62-365.pdf