MicroRNA Expression Differences in Blood-Derived CD19+ B Cells of Methotrexate Treated Rheumatoid Arthritis Patients

MicroRNA Expression Differences in Blood-Derived CD19+ B Cells of Methotrexate Treated Rheumatoid Arthritis Patients

Rheumatoid arthritis (RA) is a complex disease with a wide range of underlying susceptibility factors. Recently, dysregulation of microRNAs (miRNAs) in RA have been reported in several immune cell types from blood. However, B cells have not been studied in detail yet. Given the autoimmune nature of...

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Bibliographic Details
Main Authors: Fatima Heinicke, Xiangfu Zhong, Siri T. Flåm, Johannes Breidenbach, Magnus Leithaug, Marthe T. Mæhlen, Siri Lillegraven, Anna-Birgitte Aga, Ellen S. Norli, Maria D. Mjaavatten, Espen A. Haavardsholm, Manuela Zucknick, Simon Rayner, Benedicte A. Lie
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
miRNA
microRNA
rheumatoid arthritis
CD19+ B cells
methotrexate
NGS
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.663736/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.663736/full

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