Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer’s disease: a retrospective cohort analysis

Quantitative detection and staging of presymptomatic cognitive decline in familial Alzheimer’s disease: a retrospective cohort analysis

Abstract Background Understanding the earliest manifestations of Alzheimer’s disease (AD) is key to realising disease-modifying treatments. Advances in neuroimaging and fluid biomarkers have improved our ability to identify AD pathology in vivo. The critical next step is improved detection and stagi...

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Bibliographic Details
Main Authors: Antoinette O’Connor, Philip S. J. Weston, Ivanna M. Pavisic, Natalie S. Ryan, Jessica D. Collins, Kirsty Lu, Sebastian J. Crutch, Daniel C. Alexander, Nick C. Fox, Neil P. Oxtoby
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Alzheimer’s Research & Therapy
Subjects:
Preclinical
Neuropsychology
Familial Alzheimer’s disease
Event-based modelling
Online Access:http://link.springer.com/article/10.1186/s13195-020-00695-2

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http://link.springer.com/article/10.1186/s13195-020-00695-2

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