Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism

Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism

Abstract Objective To evaluate the taxonomic composition of the gut microbiome in gout patients with and without tophi formation, and predict bacterial functions that might have an impact on urate metabolism. Methods Hypervariable V3–V4 regions of the bacterial 16S rRNA gene from fecal samples of go...

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Bibliographic Details
Main Authors: Eder Orlando Méndez-Salazar, Janitzia Vázquez-Mellado, Carlos S. Casimiro-Soriguer, Joaquin Dopazo, Cankut Çubuk, Yessica Zamudio-Cuevas, Adriana Francisco-Balderas, Karina Martínez-Flores, Javier Fernández-Torres, Carlos Lozada-Pérez, Carlos Pineda, Austreberto Sánchez-González, Luis H. Silveira, Ana I. Burguete-García, Citlalli Orbe-Orihuela, Alfredo Lagunas-Martínez, Alonso Vazquez-Gomez, Alberto López-Reyes, Berenice Palacios-González, Gabriela Angélica Martínez-Nava
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Molecular Medicine
Subjects:
Gout
Gut microbiota
Uric acid metabolism
Online Access:https://doi.org/10.1186/s10020-021-00311-5

Internet

https://doi.org/10.1186/s10020-021-00311-5

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