MicroRNA let-7c inhibits Bcl-xl expression and regulates ox-LDL-induced endothelial apoptosis

Endothelial cells (ECs) apoptosis induced by oxidizedlow-density lipoprotein (ox-LDL) is thought to play a criticalrole in atherosclerosis. MicroRNAs (miRNAs) are a class ofnoncoding RNAs that posttranscriptionally regulate the expressionof genes involved in diverse cell functions, includingdifferen...

Full description

Bibliographic Details
Main Author: Bing Qin1, Bo Xiao1, Desheng Liang2, Ye Li1, Ting Jiang1 & Huan Yang1,*
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-08-01
Series:BMB Reports
Subjects:
Online Access:http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTIyMTdAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS04JTVEMTIwODMwMTcxOV8lMjg0NjQtNDY5JTI5Qk1CXzEyLTAzMy5wZGY=