Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2

Coordination of Candida albicans Invasion and Infection Functions by Phosphoglycerol Phosphatase Rhr2

The Candida albicans RHR2 gene, which specifies a glycerol biosynthetic enzyme, is required for biofilm formation in vitro and in vivo. Prior studies indicate that RHR2 is ultimately required for expression of adhesin genes, such as ALS1. In fact, RHR2 is unnecessary for biofilm formation when ALS1...

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Bibliographic Details
Main Authors: Jigar V. Desai, Shaoji Cheng, Tammy Ying, M. Hong Nguyen, Cornelius J. Clancy, Frederick Lanni, Aaron P. Mitchell
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Pathogens
Subjects:
Candida albicans
adherence
invasion
biofilm
intra-abdominal candidiasis
glycerol
turgor
infection
adhesin
Online Access:http://www.mdpi.com/2076-0817/4/3/573

Internet

http://www.mdpi.com/2076-0817/4/3/573

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