Reactivations of Latent Viral Infections Are Associated with an Increased Thr389 p70S6k Phosphorylation in Peripheral Lymphocytes of Renal Transplant Recipients

Reactivations of Latent Viral Infections Are Associated with an Increased Thr389 p70S6k Phosphorylation in Peripheral Lymphocytes of Renal Transplant Recipients

Reactivations of BK polyoma virus (BKPyV) and human cytomegalovirus (HCMV) frequently cause life- and graft-threatening complications after renal transplantation. Both viruses are dependent on the mTOR pathway for replication. In this study we investigated the association of viral replication with m...

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Bibliographic Details
Main Authors: Maxim Cherneha, Johannes Korth, Meike Kaulfuß, Mirko Trilling, Marek Widera, Hana Rohn, Sebastian Dolff, Nina Babel, André Hoerning, Andreas Kribben, Oliver Witzke
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
BK polyoma virus
PyVAN
human cytomegalovirus
p70 ribosomal S6 kinase
renal transplantation
Online Access:https://www.mdpi.com/1999-4915/13/3/424

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https://www.mdpi.com/1999-4915/13/3/424

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