Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

African swine fever (ASF) poses a severe threat to the global pig industry for which currently there is no available vaccine. The aetiological ASF virus (ASFV) has a predilection for cells of the myeloid lineage, however little is known about its interaction with polarised macrophages. This study fo...

Full description

Bibliographic Details
Main Authors: Giulia Franzoni, Elisabetta Razzuoli, Silvia Dei Giudici, Tania Carta, Grazia Galleri, Susanna Zinellu, Mauro Ledda, Pierpaolo Angioi, Paola Modesto, Simon P. Graham, Annalisa Oggiano
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pathogens
Subjects:
asfv
monocyte-derived macrophages
polarized activation
flow cytometry
cytokines
Online Access:https://www.mdpi.com/2076-0817/9/3/209

Internet

https://www.mdpi.com/2076-0817/9/3/209

Similar Items