Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models

Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models

Psoriasis is considered an immune-mediated inflammatory skin disorder that affects the quality of life of nearly four percent of the world population. Considering the side effects of existing therapeutic drugs and the urgent need for new drug development, we screened more than 250 traditional Chines...

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Bibliographic Details
Main Authors: Bo-Wen Jiang, Wen-Jing Zhang, Ying Wang, Li-Ping Tan, Yong-Li Bao, Zhen-Bo Song, Chun-Lei Yu, Shu-Yue Wang, Lei Liu, Yu-Xin Li
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Psoriasis
Convallatoxin
Necroptosis
Reactive oxygen species
Epidermal hyperplasia and skin inflammation model
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219352370

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http://www.sciencedirect.com/science/article/pii/S0753332219352370

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