Age-Dependent Demethylation of Sod2 Promoter in the Mouse Femoral Artery

We studied the age-dependent regulation of the expression of the antioxidant enzyme manganese superoxide dismutase (MnSOD encoded by Sod2) through promoter methylation. C57Bl/6 mice were either (i) sedentary (SED), (ii) treated with the antioxidant catechin (CAT), or (iii) voluntarily exercised (EX)...

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Bibliographic Details
Main Authors: Albert Nguyen, François Leblond, Maya Mamarbachi, Steve Geoffroy, Eric Thorin
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/8627384